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Welcome to M.S.Ramaiah Institute of Nursing Education and Research, Bangalore

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M.S.Ramaiah Insitute of Nursing Educatin and Research is Recognized by Govt. of Karnataka, Karnataka Nursing Council and Indian Nursing Council and Affiliated to Rajiv Gandhi University of Health Sciences, Karnataka.


In keeping with the spirit of independence and the euphoria it generated , Sri M.S.Ramaiah felt that he had to contribute to the much needed growth of our country. He believed that education has to be the solid base on which India should build its socio-political and economic edifice. Without adequate opportunities for professional education the ambitions and talents of many bright students were nipped in the bud. It is against this backdrop, for furthering the cause of professional education, that Sri M.S.Ramaiah established the Gokula Education Foundation (GEF) in the early sixties.

 

Gastroduodenal Mucosal Damage in Major Burns:How Significant is It?
Authors: S. Kumarage; P.A.H.A. Gunawardena; J. Hewavisenthi; K.I. Deen
Affiliation: Pathology, North Colombo General Hospital Ragama, SriLanka
Source: Gut  Vol: 50,  No: 2,  April, 2002
Abstract
Introduction: Acute gastroduodenal mucosal injury has been known to be associated with major burns. The aim of this study was to assess the incidence and rationale of giving prophylactic acid suppression treatment to all patients with major burn injury. Patients and Methods: 18 patients (13 females, median age 23 years-range 14–42)with major burn injury (Burn surface area >20%) admitted over 20 months were analysed. The aetiology was flame burns-10,hot water burnsd-5,and acid burns-3.All patients were received within 6 hours of injury. Initial fluid resuscitation was performed using Parkland regime. Non steroidal analgesics and acid suppression was not employed. All patients were subjected to upper gastrointestinal endoscopy(UGIE) between 24–72 hours after admission and antral mucosal biopsy was obtained. UGIE was repeated a week later. Histology samples were evaluated by a single blinded pathologist. Dyspeptic symptoms were sought on a daily basis. Results: 2(11.1%)Patients had mild upper abdominal pain. 2(11.1%)Patients had abnormal UGIE findings during the first endoscopy.(1-superficial gastritis,1-errosive gastritis).3(16.7%) Patients had abnormal endoscopic findings during subsequent endoscopy(2-superficial gastritis,1-erosivegastritis). No peptic ulcers were detected in any of the patients.8(44.4%) Patients had mild histological changes(7-mild acute inflammatory changes,1-chronic inflammatory changes). Conclusion: This study shows that there was no endoscopic evidence of serious gastroduodenal mucosal injury in patients with major burns. Furthermore antral mucosal histology revealed only mild inflammatory changes. The use of prophylactic acid suppression in major burns as a blanket policy may require re-evaluation.
 

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